![]() Abrupt discontinuation of any hydrocodone-containing medication in a person who has become physically dependent on it may lead to a withdrawal syndrome and symptoms such as restlessness, pupil dilation, watery eyes, and a runny nose, sweating, muscle aches, insomnia, irritability, and gastrointestinal complaints.Taper and discontinue treatment with hydrocodone if the patient engages in serious or repeated aberrant drug-related behaviors or drug abuse.Risk management strategies include written treatment agreement plans (such as contracts), urine drug testing, and other risk assessment and monitoring tools. Hydrocodone is one of the most abused opioids in the United States. ![]() Legitimate supplies of products containing hydrocodone may be sought out by drug seekers. Thoroughly evaluate patients and assess risk factors for misuse, abuse, and addiction. The risk is higher in people with psychiatric disorders.
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